The hard drive is not accessible from the outside of the computer. It is completely internal. There is a LED light, however, to let you know when the drive is being accessed. On most machines you can clearly hear the drive starting up and when the head is moving around. Each drive has a different sound.
If your drive starts making a sound that is different from normal, something is wrong. It may be a software problem that is causing the drive to hunt around too much or it may be a hardware problem. Either way something needs to be fixed.